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Malik el Djebena, who is condemned to six years in prison, cannot read or write, but soon figures out the politics of the prison. Though Malik is only 19-years-old, the leader of the Corsican gang who rules the prison corners him and gives him certain 'missions' to carry out. He quickly gains the confidence of the gang leader, as these assignments begin to toughen him up. But Malik soon develops some plans of his own.

In Paris in the early 1990s, a group of activists go to battle for those stricken with HIV/AIDS, taking on sluggish government agencies and major pharmaceutical companies. Amid rallies, protests, fierce debates and ecstatic dance parties, the newcomer Nathan falls in love with Sean, the group's radical firebrand, and their passion sparks against the shadow of mortality as the activists fight for a breakthrough.